Reports of drug resistance in the area first emerged in 2008. The problem has since spread to other parts of South East Asia. The study is published in the journal Nature Genetics.
The lead author, Dr Olivo Miotto, of the University of Oxford and Mahidol University in Thailand, said: “All the most effective drugs that we have had in the last few decades have been one by one rendered useless by the remarkable ability of this parasite to mutate and develop resistance.
“Artemisinin right now works very well. It is the best weapon we have against the disease, and we need to keep it.”